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Histiocytoma

Also Known As: Button Tumor

Transmission or Cause

A benign, usually self-limiting tumor of mononuclear white blood cells in the skin which are derived from epidermal Langerhans cells.

Affected Animals

Most common in younger (< 4yr) dogs.

Clinical Signs

Usually a single, rapidly growing raised, round, hairless pink, red or ulcerated skin nodule. They occur most commonly on the head, ears and legs.

Symptoms

See Clinical Signs.

Diagnosis

Needle aspirate and/or biopsy of the nodule reveals round cells which are typical histiocytes +/- associated inflammatory cells.

Prognosis

Good, as these tumors are benign.

Treatment

In most cases, these tumors will spontaneously regress within 2-3 months due to immune stimulation. Treatment with topical or systemic steroids is therefore unnecessary and may inhibit immune clearance of the tumors. Lesions which persist for longer than 2-3 months should be removed and biopsied, and excision is curative in these cases.

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Close-up of a dog's eyelid with a histiocytoma tumor at a veterinary dermatology clinic in Lacey